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Dietary polyphenols have received enormous attention from scientists and nutritionists due to their well-known role in human health, because they can help to prevent degenerative diseases such as cancer, CVD, and neurological disorders [62], and their therapeutic effects are based on the regulation of cellular signaling pathways [63,64]
The transcriptomic divergence could simply reflect the difference between acute chemical shock and steady-state adaptation
Im thinking I need to revisit info like this on MTHFR, maybe now there is more info and treatment ideas
Activation of the SIRT1/PGC-1 pathway was identified as a critical factor in this process, supporting the hypothesis that UroAs effects on mitophagy play a key role in its ability to improve muscle health (Reference Andreux, Blanco-Bose and Ryu14)
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