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Mouse models are highly effective in age related studies as the shortened timeline allows observation of the full impact of treatments in months as opposed to the years of human clinical trials

Although SCD is rare, its symptoms typically begin with sensory disturbances in the hands, followed by reduced vibration sense, ataxic gait, and pathological reflexes such as hyperreflexia and a positive Babinski sign [4]

Over the past twenty years, number of investigations has been carried by different research groups to establish the role of 5ARI in the management of prostate cancer [44]

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