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Therefore, although high concentrations of cytokines inhibit the production of red blood cells and reduce the consumption of plasma iron, the generation of nontransferrin-bound iron required for pathogen growth also decreases, leading to an increase in copper content but a decrease in the iron level in peripheral blood [204]

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Although cleavable linkers are designed to be stable in circulation, they are diverse and can bind to a wider variety of payloads

2019;11(10):E2298