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One expert noted that TB-500 was found to accelerate tumor growth in animal experiments, that other growth-related peptides might carry the same risk, and that other peptides could cause hormonal imbalances

10.1097/hco.0000000000000562

It presents with lower urinary tract symptoms, such as dysuria, dyspareunia, increased urinary frequency (often up to 60 times a day) and urinary urgency without urinary tract infection lasting for at least 6 weeks, causing pelvic pain and pressure or discomfort related to bladder filling