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These heterogeneous responses are modulated by multiple factors, including tumor classification, study methodology, treatment duration, and patient-specific parameters (Table 1)

Antibiotics promote the sampling of luminal antigens and bacteria via colonic goblet cell associated antigen passages

A meta-analysis found GLP1RAs exhibit antidepressant effects, particularly in T2D, with liraglutide showing notable efficacy over exenatide, though subgroup differences were not significant 62

Tesamorelin reduces deep abdominal fat by roughly 1518% in 26 weeks, measured by MRI, in placebo-controlled trials, without dieting