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Its contraindicated in individuals with a personal or family history of certain thyroid cancers and multiple endocrine neoplasia syndrome type 2

The CDCs report, Projected Number of People with Dementia in the United States 20152060, published in Alzheimers & Dementia (2019), states that people with diabetes have a 50% higher chance of developing dementia due to vascular complications

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Clinical improvement based on the quartile grading scale at the end of treatment did not show any statistically significant difference between groups