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These direct comparisons allowed a more sensitive differentiation of HR effects, and confirmed that lixisenatide induces a significantly smaller increase in mean 24-h HR compared with liraglutide (4 vs

Figure 2 A fundamentally important debate in the field revolves around the outside-in (whereby a primary defect in the peripheral immune system promotes invasion of the CNS by autoreactive immune cells) vs

the study mentioned earlier noted a higher incidence of thiamine deficiency at 12 months in GLP-1 RA users compared to those not on these drugs, although its not extremely common

P.SunagawaS.BahramM.GoeserF.et al