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While the Phase 2 trial did not specifically stratify outcomes by baseline eGFR, GLP-1 receptor agonists as a class have demonstrated renoprotective effects in at-risk populations

NMR-based metabolomics data analysis 2D HSQC and TOCSY spectra were uploaded to the new COLMARq web server ( for peak picking, peak alignment, metabolite identification, metabolite quantification via Gaussian peak fitting, spectral normalization via global scaling based on the average, median 30% peak volume ratios between an arbitrarily selected reference spectrum, and univariate statistical analysis between cohorts (51, 52)