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Mioduchoski, FNP-BC is a board-certified Family Nurse Practitioner with experience in critical care, medical weight loss, hormone optimization, regenerative medicine, and wellness-focused telehealth care

doi: 10.1016/S0021-9258(19)75835-9 40 KirkmanHNRolfoMFerrarisAMGaetaniGF

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Rat model of 3-NP toxicity Male Lewis rats (weighing 260-300g) fed with either an unsupplemented control diet or a diet supplemented with 2% creatine or 1% CoQ 10 or a combination of the two for one week were implanted subcutaneously with osmotic minipumps (Model 2ML1, Alzet, Cupertino CA, filled with 3-NP 70mg/ml in PBS, pH 7.4) that delivered 3-NP 50mg per kg bodyweight daily for 7 days while remaining on the same diets (Ouary et al