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Whilst GLP-1 receptor agonists slow the digestive process, there is no substantial evidence that they significantly impair nutrient absorption in individuals with normal pancreatic function

CrossRef Comparison of Diabetic Polyneuropathy and Cardiac Autonomic Neuropathy in Type 1 and Type 2 Diabetes Mellitus Laura iaulien, Ieva Sereik, Juozas Rimantas Lazutka, Joana Semigrejeviene, ydrn Visockien Diabetology.2025

9 It acknowledges the importance of individualising treatment according to the presence of cardiovascular risk and comorbidities (especially heart failure and CKD) and gives a broad choice of options for dual or triple therapy

For genetic perturbations that confer fitness defects, a negative -score defines synthetic sick and a positive -score defines buffering, respectively (Supplementary Data 3)