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Weekly formulations should be administered on the same day each week, while daily formulations should be given at approximately the same time each day

Higher doses may intensify side effects such as nausea or restlessness, which can disrupt sleep in sensitive individuals

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Furthermore, RJ contains free amino acids such as methionine, proline, cysteine and cystine might responsible for this effect by promoting biosynthesis of glutathione and scavenging free radicals, in addition to the ability of RJ to enhance the activity of antioxidant enzymes 35