While some individual ingredients, such as berberine, have modest evidence of weight loss when taken orally at therapeutic doses, there is no evidence that meaningful amounts can be delivered through skin patches
What Is Vitamin B12 and Why Do You Need It
As shown in Figure 9B, the common targets of main ingredients and AD in FRP are mainly enriched in signal transduction, positive regulation of transcription from RNA polymerase II promoter, protein phosphorylation, negative regulation of the apoptotic process, response to the drug, positive regulation of gene expression, positive regulation of cell proliferation, response to xenobiotic stimulus, positive regulation of transcription, DNA-templated, positive regulation of MAPK cascade
This can cause your skin to dry out