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Conditions that prevent use include a personal or family history of medullary thyroid carcinoma, Multiple Endocrine Neoplasia syndrome type 2, a history of severe pancreatitis, pregnancy, and active gallbladder disease

Patsy Healey's concept that futures are 'path contingent' rather than strictly 'path dependent' emphasises the importance of examining specific experiences and their relevance in various contexts rather than adhering only to generalised universal principles