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It should be used in conjunction with lifestyle changes, such as exercise and healthy food choices

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High-fat-fed ApoE / mice exhibit larger atherosclerotic plaques, severe ferroptosis, increased NOX production, and reduced GSH and xCT expression in the thoracic aorta compared to wild-type mice (Li et al., 2021)

Everything before that point is considered perimenopause: the phase when estrogen and progesterone levels begin to decline, but periods still occur, though often irregularly