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Proteins were visualized using the Supersignal West Pico Chemiluminescent Substrate system (Pierce, Fenton, MO) and molecular weights determined by comparison to protein ladders (BenchMark, Invitrogen
These drugs, currently sold by Novo Nordisk and Eli Lilly and Company, have raked in hundreds of billions of dollars in sales
The SURPASS program established efficacy in type 2 diabetes across multiple comparators, including head-to-head superiority versus semaglutide on HbA1c reduction in SURPASS-2 (Fras et al., NEJM, 2021)
Hochberg Y, Benjamini Y
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