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Electroconvulsive Therapy (ECT) increases serum Brain Derived Neurotrophic Factor (BDNF) in drug resistant depressed patients

This paper demonstrates that c-Myb transcriptionally regulates CDO1 and inhibition of CDO1 expression upregulates GPX4 (Hao et al., 2017)

Thus, in children with Down syndrome no special changes in the anti-oxidant system seem to have been produced to compensate for the higher levels of reactive oxygen species