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Differences in the insulin titration rules were also observed across the studies, with various insulin algorithms being used such as treat-to-target, Initiate Insulin by Aggressive Titration and Education, titration at the investigators discretion, or capping of basal insulin dose at a level equal to the pre-study level

This convenient injectable peptide delivery method supports better treatment adherence and offers ease of use for patients managing weight loss or type 2 diabetes

Paracetamol may help manage mild to moderate body aches

2) Hormonal interactions: oestrogen may synergise with GLP-1 RAs to enhance appetite regulation by activating brain regions involved in controlling food intake and modifying reward pathways [55, 56]