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Rotate injection sites : Alternate between abdomen, thigh, and upper arm to reduce injection site reactions

Generally, hypoxia itself can trigger angiogenesis by upregulating vascular endothelial growth factor (VEGF), hypoxia-inducible factor 1 (HIF1), T-cell intracellular antigen 1 (TIA1), eukaryotic translation initiation factor 2 (elF2), and thrombospondin (TSP1) [31]

In summary, we put forward that targeting mature OLs is an untapped therapeutic avenue to support CNS health in the context of neurological disorders

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