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Type 2 Diabetes (since 2009) Obesity treatment (since 2014) Cardiovascular outcomes and kidney trials ongoing Current research includes Alzheimers trials and other neurocognitive disorders | | Drug Examples: Liraglutide , Semaglutide | These GLP-1 receptor agonists are now being studied for their potential to cross the blood-brain barrier and exert neuroprotective effects, possibly mitigating oxidative stress and mitochondrial dysfunction associated with neurodegenerative diseases

Esterlis, I

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Conversely, glutathione reductase (Gsr), heme oxygenase 1 (Hmox1), glucose transporter member 5 (Glut5) and lipoprotein lipase (Lpl) were increased during the dark, or active period, suggesting that microglia have increased nutrient uptake during the active period