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Despite this relatively short half-life, there are reports of increased mortality in mosquitoes feeding on the treated host up to 28 days after the administration of ivermectin when 300 g/kg a day 3 days in a row is given, which may be due to ivermectin metabolites that continue to circulate post-ivermectin clearance (Smit et al

Due to their various molecular skeletons, pharmacological characteristics and dosing schedules, different DPP-4is could display widely divergent results when compared with acarbose

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