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However, this minimum value may not be the global minimum of the loss function, which corresponds to the smallest value of the loss function across the entire parameter space

Considering the widespread expression of GLP-1 receptors in the brain, the authors recommend that future studies should focus on identifying the key neurocircuits involved in mediating the effects of GLP-1 receptor agonists on substance use disorder, as well as determine the specific patient subtypes who are most likely to benefit from these treatments

Laboratory investigations contribute to the broader scientific understanding of peptide structure, stability and molecular interactions