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During the physical examination, your doctor will look for a red, beefy tongue, pale or yellowish skin, a rapid pulse, and heart murmurs resulting from an anemia-related increase in blood flow demands on the heart

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doi:10.3389/fphar.2022.972468

Intriguingly, emerging evidence suggests that some newer agents such as ocrelizumab (a B cell-depleting monoclonal antibody) and siponimod (a sphingosine 1-phosphate receptor modulator with anti-inflammatory and neuroprotective properties) are beneficial in progressive MS, potentially with effects independent of suppressing acute inflammation (Montalban et al., 2017