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Efficacy and safety of once-weekly semaglutide 20 Mg versus 10 Mg in patients with type 2 diabetes (sustain forte): A double-blind, randomised, phase 3B trial
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Hypoglycemia risk Although the risk of hypoglycemia with these medications is generally low, combining them could potentially increase this risk, especially in patients also taking insulin or sulfonylureas
doi: 10.2337/db21-0848 Summary Keywords GLP-1 - glucagon-like peptide-1, GIP - glucose-dependent insulinotropic peptide, obesity, incretin, pharmacology Citation Douros JD, Flak JN and Knerr PJ (2025) The agony and the efficacy: central mechanisms of GLP-1 induced adverse events and their mitigation by GIP
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