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Similar content being viewed by others Introduction Tyrosinemia type I (hepatorenal tyrosinemia, HT-1) is an autosomal recessive condition (OMIM 276700) resulting in hepatic failure with comorbidities involving the renal and neurologic systems (for a comprehensive review, see Mitchell et al

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Memory and learning depend on healthy synapses, and proteins that maintain those synapses tend to decline with age

A significant reduction in epididymal fat mass was quantified at endpoint after RETA and reflected by an almost ablated concentration of circulating leptin, whereas after RETA withdrawal, white adipose mass and leptin concentrations were partially reversed compared to Veh (Fig