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In England, access is typically through specialist weight management services (tier 3 or 4), with specific BMI thresholds for eligibility, and treatment is usually limited to up to 2 years

Statistical significance was determined by two-way ANOVA followed by Bonferroni post-hoc analysis

Subsequent investigations have revealed that Nrf2-dependent autophagy activation disrupts the binding of SLC7A11 with BECN1 phosphorylated at S93 and augments the membrane translocation of SLC7A11 to counteract ferroptosis