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Consequently, there was a selective reduction in malignant prostate cell proliferation, a decrease in intracellular succinate levels, and compromised cellular respiration [160]

Symptoms include: Persistent fatigue and lack of motivation Decreased libido or erectile dysfunction Loss of muscle mass and strength Weight gain and slower metabolism Mood changes, irritability, and poor focus Reduced bone density A meta-analysis published in Clinical Endocrinology confirmed that TRT significantly increases lean body mass and decreases fat mass in hypogonadal men (Corona et al., 2016)

November 2023: In a price-fixing class action, Gilead reached a $246.75 million preliminary settlement with plaintiffs claiming that the company conspired with a drug manufacturer to delay the release of generic versions of their HIV drugs

Some users notice weight loss within a few weeks, but results can vary based on individual health factors and adherence to treatment