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Like Taylor-Williams, people have reported experiencing mood changes or irritability, which can lead to a lower sex drive or complete lack or need for physical intimacy

The dual incretin mechanism GLP-1 receptor agonists engage the GLP-1 receptor across the pancreas, hypothalamus, and gastrointestinal tract, slowing gastric emptying, blunting post-meal glucose spikes, reducing appetite, and increasing satiety signaling

Theoretically, they operate through different mechanisms: semaglutide suppresses appetite and slows gastric emptying via GLP-1 receptors, while AOD 9604 acts on beta-3 adrenergic receptors on fat cells

DSIP is even being studied as a potential target for treating major depressive disorder