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By acting as a hepatocyte growth factor (HGF)/c-Met agonist, it promotes neuroplasticity, memory formation, and potential repair of damaged neural circuits

Its defined structure and receptor selectivity make it ideal for controlled experimental models focused on studying endocrine pathways

Convenient and high-throughput

Efficacy Benefits of DHE and Precision Olfactory Delivery (POD) technology 1,2 In 4 randomized, double-blind, placebo-controlled studies (N=605) of a traditional dihydroergotamine mesylate (DHE) nasal spray product, 30% to 61% of patients had mild or no pain at 2 hours 1 Trudhesa with advanced POD technology consistently delivered DHE without the initial peak concentration of intravenous (IV) DHE 2 Trudhesa demonstrated rapid, sustained, consistent relief, even when taken late into an attack 2,3 * *Based on a phase 3, open-label, safety study evaluating exploratory efficacy outcomes and post hoc analyses