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9258), anti-phosphoJNK (no

Within the hypothalamus, GLP-1 interacts with pro-opiomelanocortin (POMC) neurons in the arcuate nucleus (it seems to have limited direct access here), a classic site involved in appetite regulation and energy expenditure

Secondly, youre going to see the drugs that are going to be approved and developed are drugs that are going to be informed by contemporary disease models that are not focusing on the almighty monoamines primarily, but are focusing on what you and I chatted about, aspects like metabolism, but theres other mechanisms as well, like inflammation

And for GLP-1 drugs, those starting materials come with some particular challenges