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1C), but a partial Arr agonist (Fig

Symptoms can range from obvious to subtle and include: External bleeding signs: Unexplained bruising Frequent or hard-to-stop nosebleeds Bleeding gums during brushing Cuts that take longer than usual to stop bleeding Internal bleeding warning signs: Dark, tarry stools or bright red blood in stool Vomiting blood or material resembling coffee grounds Severe headaches or dizziness Extreme fatigue or weakness Heavy menstrual bleeding (for women) Management Strategies To reduce risks, your healthcare provider will likely check your prothrombin time and INR more frequently when you start or adjust GLP-1 medications

While they may cause modest increases in heart rate (typically 2-4 beats per minute) and modest decreases in blood pressure, they do not significantly raise core body temperature or substantially accelerate metabolic rate