"With the approval of the Wegovy pill, patients now have access to a once-daily oral option that delivers weight loss results comparable to injectable Wegovy," said Mike Doustdar, President and CEO of Novo Nordisk, in the company's official statement
Lack of access often leads patients to switch to less effective alternatives or discontinue treatment entirely. Beyond blood sugar control, Novo Nordisk also states that the Ozempic pill is also approved for reducing the risk of major cardiovascular events, including heart attack, stroke, or death, in adults with type 2 diabetes who are at elevated risk
Of note are the preferential distributions of the transsulfuration pathway and the catabolizing enzyme glycine N-methyltransferase in mammalian tissues such as liver and kidney (Finkelstein, 1990)
doi:10.1016/j.jaip.2019.07.003 9Rose M, Vogrin S, Chua KYL, et al