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Appetite and weight changes drive many lab moves, with 75% of patients reporting decreased appetite and clinical trials showing an average 10% body weight reduction over 68 weeks, which explains the typical improvements in glucose and lipid levels

Over time, however, the body adapts

Many people notice appetite changes weeks before the scale really moves

For example: A patient with high fasting insulin may respond differently than one with pancreatic beta-cell dysfunction A patient with fatty liver disease may experience additional metabolic benefitsor complicationsdepending on hepatic status This is precisely why baseline lab testing is not optionalit is foundational