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The cells treated with Sp showed slight enhancement in levels of GSH (~1.2 fold), together with minor alterations in GSSG levels, compared to untreated samples which exhibited higher GSSG content, thus indicating efficient recycling of GSSG to GSH (Fig

Considering the reduced levels of GSH and changes in the activity of GSHassociated enzymes in MS, maintaining or retrieving GSH levels might be a promising therapeutic strategy to improve the health status of patients with MS

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