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BPC-157 is derived from a gastric peptide fragment, TB-500 is a synthetic analog of thymosin beta-4 studied for actin-related processes, GHK-Cu is a copper-binding tripeptide frequently examined in extracellular matrix and biomarker research, and KPV is a short peptide fragment explored in preclinical settings for immunomodulatory signaling pathways

While further research is needed to clarify the causal pathways, the potential role of autoimmunity as a driver of persistent symptoms should not be overlooked in clinical practice

Schizophr Bull 35:549562

Colchicine also has a major role when patients begin therapy with allopurinol (see below) to prevent the increase in gout attacks that can happen when allopurinol is begun