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However, the effect (using 500mg a day dosing) was small only a drop in blood uric acid level of about 0.5 mg/dL, and almost all gout patients need to come down more than this to get to the goal of less than 6.0 mg/dL

[DOI] [PMC free article] [PubMed] [Google Scholar] [108].Costa MC, Silva G, Ramos RV, Staempfli HR, Arroyo LG, Kim P, et al

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In the absence of reduced cysteine, the addition of an acetyl group to cysteine (N-acetyl-cysteine [NAC]) provides the ability for a molecule to cross the cell membrane and promotes intracellular glutathione synthesis.[117] It is synthesized in cytosol outside the ribosomes that requires ATP, but does not require the participation of RNA