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Patients on tirzepatide lost an average of 20.2% of their body weight over 72 weeks Patients on semaglutide lost an average of 13.7% of their body weight over the same period 47% more tirzepatide patients achieved 25% or greater body weight loss compared to semaglutide Tirzepatide also produced greater reductions in waist circumference across all dose comparisons A 2024 meta-analysis published in JAMA Internal Medicine analyzing real-world data from over 140,000 patients confirmed the same pattern: tirzepatide produced an average of 4.23 kg more weight loss than semaglutide across all doses and durations studied

The 19-page order, filed on July 31, 2024, details what documents will be produced by defendant Novo Nordisk in the Ozempic Lawsuit

[31] In February 2018, authorization was granted in the European Union, [16] [84] in March 2018 in Japan, [32] and in August 2019 in Australia