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Histopathological study by H&E as well as immunohistochemical staining for detection of iNOS and eNOS markers expression in the thyroid gland and PCNA were done

Yes, often, though the direction varies

Efficacy and safety profile of exenatide once weekly compared with insulin once daily in Japanese patients with type 2 diabetes treated with oral antidiabetes drug(s): results from a 26-week, randomized, open-label, parallel-group, multicenter, noninferiority study