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Among other genes involved in GSH metabolism, glutathione transferase M2-2 ( Gstm2 ), which is suggested to prevent the neurotoxic effects of DA oxidation on dopaminergic neurodegeneration in Parkinsons disease 31 , was significantly downregulated by 8 months (Fig

But that acceleration still operates on biological timelines measured in weeks, not days

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Nicotinamide N-methyltransferase as a potential therapeutic target in metabolic and related diseases