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For scientists and industry observers, the clinical development of cagrilintide provides valuable insights into amylin biology, receptor pharmacology, and the broader field of peptide-based metabolic research, regardless of the outcome of ongoing regulatory evaluations

The innate immune system not only serves as the first line of defense but also shapes adaptive immune responses through cytokine and chemokine secretion, co-stimulatory signals, and direct immune cell interactions ( Figure 3 )