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In addition, HSF1 has also been reported to be critically involved in ferroptosis by inducing HSPB1 expression [28]

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An RCT in 50 infertile men found that NAC (600 mg/day for 3 months) significantly improved sperm concentration, motility, and morphology and reduced oxidative stress markers (Ciftci et al., Urology, 2009) [69]