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Number of animals per group and timepoint: For the 300 mg/kg APAP cohort, control and LKO mice were analyzed at 0 h ( n = 4 control, 5 LKO), 6 h ( n = 4 control, 6 LKO), 12 h ( n = 6 control, 4 LKO), 24 h ( n = 7 control, 5 LKO), 48 h ( n = 4 control, 4 LKO), 72 h ( n = 4 control, 4 LKO), and 96 h ( n = 3 control, 4 LKO)

Anaerotignum faecicola and Bacteroides stercoris were associated with a decreased B/C ratio

LY3437943, a Novel Triple GIP/GLP-1/Glucagon Receptor Agonist, Shows Glucose-Lowering and Body Weight-Lowering Efficacy After Single-Dose Administration in Type 2 Diabetes Patients

Weight loss accelerates to roughly 3-5% from baseline by the end of week 8