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However, the clinical application of Cap is hindered by its poor solubility and low oral bioavailability, which may result in adverse effects, including gastric ulcers, stomatitis, vomiting, and diarrhea [59]

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The large range of values for the slope's CI (-2.72 to -0.25) indicates a high level of uncertainty in the estimate, which is probably attributable to the small sample size (42, 43)

doi: 10.1007/s11033-025-10261-4 76 ZhaoCWuSWangH