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Modulation of Autoantibodies : Cellular Therapy and Stem Cells for Graves disease may influence the production and activity of autoantibodies, such as thyroid-stimulating immunoglobulins (TSIs), involved in stimulating thyroid hormone secretion

Interestingly, unlike other MAPKs, such as ERK1/2 and JNK1/2, it has been shown that p38 phosphorylates NRF2 and promotes its association with KEAP1, thereby preventing its nuclear translocation

Professional administration minimizes adverse events, though careful monitoring remains essential for rare cases of dermal reactions or allergic responses 15

This highly selective brain distribution of the transporter provides a solid basis for targeting the transporter to develop brain selective agents