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The LES is a muscular valve that normally keeps stomach contents where they belong

Performing a preoperative assessment of RGC using point-of-care gastric ultrasound in patients continuing GLP-1RA or GIP/GLP-1RA therapy has been suggested by experts and professional societies as a risk mitigation strategy to reduce the potential for aspiration and enhance perioperative safety [17, 28, 43]

In pharmacology, amylin action is explained through amylin receptor complexes , which are formed when the calcitonin receptor (CTR) pairs with a receptor activity modifying protein (RAMP1, RAMP2, or RAMP3)