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At the same time, it appears not to alter FSH, LH, prolactin, or TSH across evaluations of cell cultures in laboratory settings, with only minimal actions on ACTH and cortisol

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The heart tissue was minced and homogenized in the isolation medium in a ratio of 1:9, which contained (mmol/l): sucrose250, EDTA1, Tris-HCl25, pH 7.4

Further studies documented that NTBC was a potent inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPD), which catalyzes conversion of 4-hydroxyphenylpyruvate to homogentisic acid 53 (Figure 1)