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The impact of insulin-dependent diabetes on ventilatory control in the mouse

One interpretation of these findings is that subsets of typical POMC neurons may undergo shifts in their functional identity, leading to changes in the expression of the molecular machinery that enables responses to peripheral metabolic signals following exposure to obesogenic stimuli in adulthood, and hence accumulation of atypical Ghost neurons [46]

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For in vivo studies, the choice of administration route should be guided by the specific research question local administration studies can examine site-specific repair biology, while systemic administration studies examine the capacity for circulating BPC-157 to produce tissue repair effects at sites distant from the injection site