week 2 of semaglutide Wegovy Bellevue (Semaglutide) Week 2 on GLP-1s: What

Novos higher dose oral Semaglutide: ~15% weight loss but there are concerns around its side effect profile relative to injectables (and therefore persistence) Even more in the pipeline: Pfizer, Structure Therapeutics, Sciwind Biosiences, AstraZeneca Two quick notes on orals: Because of the way oral GLP1s are digested, they need far more API (active pharmaceutical ingredient) to make them

Salusins: newly identified bioactive peptides with hemodynamic and mitogenic activities

That can make it hard to stay regular, especially when youre eating less

Additionally, reduced fluid intake sometimes accompanies appetite suppression, leading to dehydration and dryness