This makes it suitable for long-term use in anxious cats or for situational stress (such as travel, introductions of new pets, new cats in the neighborhood, changes in the home, cattery visits, etc)
Over time, their skin becomes dull and uneven, impacting confidence
Particular caution should be exercised when using this formulation in conjunction with nitroglycerin or other medications that affect blood flow and oxygenation, as glutathione may influence the efficacy of these drugs
The mechanisms behind these effects are unclear, but salicylate seems to have effects centrally on GABAergic neurotransmission [203, 204], as well as more peripherally by affecting cochlear function [200, 204]