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7 Novel and Emerging Therapies One approach to avoiding gastrointestinal toxicity of NSAIDs is to pair them with fixed doses of gastroprotective agents in single-tablet formulations

GSH not only neutralizes reactive oxygen species (ROS), but can also promote chemoresistance by forming GSH-xenobiotic conjugates that are pumped out of the cell via multiple resistance-associated protein transporters (MRP) 22

Existing in all the organelles, the AsA-GSH pathway protects the cell from the toxic effects of ROS generated under a variety of abiotic and biotic stresses (Anjum et al., 2)