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This is progressive loss of medication effectiveness despite maintained dosing

investigator-initiated educational grants from Janssen Canada, Otsuka Canada outside the submitted work

If you wait too long to engage your provider, you may have to go all the way back to your initial starting dose. If your dose is not currently available Sometimes, manufacturer shortages force a treatment gap beyond your control

This deficiency can lead to megaloblastic anemia, where the body produces large, abnormal red blood cells that cannot function effectively, resulting in symptoms such as fatigue, weakness, and neurological issues